[KD Validated] Frataxin/FXN Rabbit mAb,ABclonal,A28029

Reactivity

Human

Application

WB, IF/ICC, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB035638501

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

Name[KD Validated] Frataxin/FXN Rabbit mAb
Cat. No.A28029
Accession NumberQ16595
Gene ID (Entrez)2395
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IF/ICC, IHC-P, ELISA
Working DilutionsWB:1:2500 - 1:10000 | IF/ICC:1:100 - 1:200 | IHC-P:1:200 - 1:800 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC70964
Molecular Weight15kDa/19kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

Synonyms

FA; X25; CyaY; FARR; FRDA

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