[KD Validated] MCCC1 Rabbit mAb,ABclonal,A25002

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, IP, ELISA

Conjugate

Unconjugated

Platform ID

BAB849494100

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

Name[KD Validated] MCCC1 Rabbit mAb
Cat. No.A25002
Accession NumberQ96RQ3
Gene ID (Entrez)56922
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, IP, ELISA
Working DilutionsWB:1:1000 - 1:5000 | IF/ICC:1:50 - 1:200 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC63817
Molecular Weight70kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Synonyms

MCCA; MCC-B; MCCCalpha; [KD Validated] MCCC1

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