[KD Validated] METTL3 Rabbit mAb,ABclonal,A26858

Reactivity

Human, Mouse, Rat

Application

WB, IP, IF/ICC, IHC-P, ChIP, ELISA

Conjugate

Unconjugated

Platform ID

BAB095221152

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

Name[KD Validated] METTL3 Rabbit mAb
Cat. No.A26858
Accession NumberQ86U44
Gene ID (Entrez)56339
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, IF/ICC, IHC-P, ChIP, ELISA
Working DilutionsWB:1:5000 - 1:10000 | IP:0.5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells | IF/ICC:1:200 - 1:400 | IHC-P:1:800 - 1:3200 | ChIP:5 μg antibody for 10 μg-15 μg of Chromatin | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC66900
Molecular Weight75 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Synonyms

M6A; IME4; Spo8; MT-A70; hMETTL3

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