[KD Validated] RIPK1/RIP Rabbit mAb,ABclonal,A19580

Reactivity

Human

Application

WB, IP, ELISA

Conjugate

Unconjugated

Platform ID

BAB100018848

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

Name[KD Validated] RIPK1/RIP Rabbit mAb
Cat. No.A19580
Accession NumberQ13546
Gene ID (Entrez)8737
RRIDAB_2862680
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IP, ELISA
Working DilutionsWB:1:1000 - 1:2000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC0059
Molecular Weight76kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.

Synonyms

RIP; RIP1; AIEFL; IMD57; RIP-1; RIPK1/RIP

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