[KD Validated] TRADD Rabbit mAb,ABclonal,A27817
Reactivity
Human, Mouse, Rat
Application
WB, IP, ELISA
Conjugate
Unconjugated
Platform ID
BAB353742060
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
Name[KD Validated] TRADD Rabbit mAb
Cat. No.A27817
Accession NumberQ15628
Gene ID (Entrez)8717
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, ELISA
Working DilutionsWB:1:2500 - 1:10000 | IP:0.5μg-4μg antibody for 500μg-700μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC66711
Molecular Weight35 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Synonyms
Hs.89862
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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