KIFAP3 Antibody (YA2769),MedChemexpress,HY-P83024

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by The related gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. The protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and The phosphorylation reduces the affinity of the protein for smg GDS. It is thought that The protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for The related gene.

KAP3; KIF3AP; Kifap3; Kinesin associated protein 3; SMAP