KIRAVIA Blue 520™ anti-human CD14 Antibody, CX3CR1, K0124E1,BioLegend,355712

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB116233590

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameKIRAVIA Blue 520™ anti-human CD14 Antibody, CX3CR1, K0124E1
Cat. No.355712
HostMouse
RRIDAB_3683379 (BioLegend Cat. No. 355711)AB_3683379 (BioLegend Cat. No. 355712)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberK0124E1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCX3CR1
ImmunogenDNA vaccine with the full coding sequence of human GPCR cloned in expression vector.
PurityThe antibody was purified by affinity chromatography and conjugated with KIRAVIA Blue 520™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also known as GPR13 or V28. It is expressed on NK cells, T cell subset, monocytes/macrophages, dendritic cells, and some malignant epithelial cells. CX3CL1 (known as fractalkine, neurotactin) is the ligand of CX3CR1. CX3CL1 is a unique transmembrane molecule with a CX3C-motif chemokine domain and a mucin-like stalk. CX3CL1 is expressed by activated-endothelial cells, neurons, and astrocytes. The interaction of CX3CR1 and its ligand mediates cell firm adhesion and migration.

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