[KO Validated] ATG5 Rabbit mAb,ABclonal,A19677

Reactivity

Human, Mouse, Rat

Application

WB, IF-P, IHC-P, IP, ELISA

Conjugate

Unconjugated

Platform ID

BAB281265601

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Name[KO Validated] ATG5 Rabbit mAb
Cat. No.A19677
Accession NumberQ9H1Y0
Gene ID (Entrez)9474
RRIDAB_2862728
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF-P, IHC-P, IP, ELISA
Working DilutionsWB:1:1000 - 1:6000 | IF-P:1:200 - 1:400 | IHC-P:1:200 - 1:2000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC0156
Molecular Weight55kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

Synonyms

ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE; G5

Category Paths

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