[KO Validated] CPT1A Rabbit mAb,ABclonal,A22899

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB468809330

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Name[KO Validated] CPT1A Rabbit mAb
Cat. No.A22899
Accession NumberP50416
Gene ID (Entrez)1374
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, ELISA
Working DilutionsWB:1:1000 - 1:2000 | IHC-P:1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC3148
Molecular Weight88 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 40% glycerol, pH7.2.
Regulatory StatusResearch Use Only

Scientific Background

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

CPT1; CPT1-L; L-CPT1; CPT1A

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