[KO Validated] GRK2 Rabbit mAb,ABclonal,A4443

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB781515481

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

Tel:
Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Name[KO Validated] GRK2 Rabbit mAb
Cat. No.A4443
Accession NumberP25098
Gene ID (Entrez)156
RRIDAB_2863276
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, ELISA
Working DilutionsWB:1:1000 - 1:3000 | IF/ICC:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC1013
Molecular Weight80 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.

Synonyms

BARK1; ADRBK1; BETA-ARK1; K2

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