[KO Validated] GSDME (Full Length+N terminal) Rabbit mAb,ABclonal,A28230

Reactivity

Human

Application

WB, IP, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB470308610

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

Name[KO Validated] GSDME (Full Length+N terminal) Rabbit mAb
Cat. No.A28230
Accession NumberO60443
Gene ID (Entrez)1687
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IP, IHC-P, ELISA
Working DilutionsWB:1:3000 - 1:10000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | IHC-P:1:100 - 1:400 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000),a sequential dilution method is strongly recommended to ensure measurement accuracy.
Clone NumberARC77793
Molecular Weight35 kDa/55 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

Synonyms

DFNA5; ICERE-1

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