[KO Validated] GSK3β Rabbit mAb,ABclonal,A27666
Reactivity
Human, Mouse, Rat
Application
WB, IP, IF-P, ELISA
Conjugate
Unconjugated
Platform ID
BAB115311504
ABclonal
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Product Specifications
Scientific Background
Specifications
Name[KO Validated] GSK3β Rabbit mAb
Cat. No.A27666
Accession NumberP49841
Gene ID (Entrez)2932
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, IF-P, ELISA
Working DilutionsWB:1:5000 - 1:20000 | IP:0.5μg-4μg antibody for 300μg-500μg extracts of whole cells | IF-P:1:200 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000)，a sequential dilution method is strongly recommended to ensure measurement accuracy.
Clone NumberARC70826
Molecular Weight46 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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