[KO Validated] NF-kB p65/RelA Rabbit mAb,ABclonal,A19653

Reactivity

Human, Mouse, Rat, Monkey

Application

WB, IHC-P, IF/ICC, ELISA, ChIP

Conjugate

Unconjugated

Platform ID

BAB343746860

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Name[KO Validated] NF-kB p65/RelA Rabbit mAb
Cat. No.A19653
Accession NumberQ04206
Gene ID (Entrez)5970
RRIDAB_2862717
IsotypeIgG
ReactivityHuman, Mouse, Rat, Monkey
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, ELISA, ChIP
Working DilutionsWB:1:5000 - 1:20000 | IHC-P:1:2000 - 1:8000 | IF/ICC:1:600 - 1:2400 | ChIP:5μg antibody for 10μg-15μg of Chromatin | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC51086
Molecular Weight65kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Synonyms

p65; CMCU; NFKB3; AIF3BL3; NF-kB p65/RelA

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