[KO Validated] RIPK1/RIP Rabbit mAb,ABclonal,A28395

Reactivity

Human

Application

WB, IP, ELISA

Conjugate

Unconjugated

Platform ID

BAB343846812

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

Name[KO Validated] RIPK1/RIP Rabbit mAb
Cat. No.A28395
Accession NumberQ13546
Gene ID (Entrez)8737
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IP, ELISA
Working DilutionsWB:1:16000 - 1:56000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000),a sequential dilution method is strongly recommended to ensure measurement accuracy.
Clone NumberARC77515
Molecular Weight76 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.

Synonyms

RIP; RIP1; AIEFL; IMD57; RIP-1

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