[KO Validated] SIRT3 Rabbit mAb,ABclonal,A22409
Reactivity
Human
Application
WB, ELISA
Conjugate
Unconjugated
Platform ID
BAB031640421
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
Name[KO Validated] SIRT3 Rabbit mAb
Cat. No.A22409
Accession NumberQ9NTG7
Gene ID (Entrez)23410
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:1000 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC51535
Molecular Weight28kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control.
Synonyms
SIR2L3; T3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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