[KO Validated] SIRT3 Rabbit mAb,ABclonal,A20805
Reactivity
Human, Rat
Application
WB, IHC-P, IP, ELISA
Conjugate
Unconjugated
Platform ID
BAB281165649
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
Name[KO Validated] SIRT3 Rabbit mAb
Cat. No.A20805
Accession NumberQ9NTG7
Gene ID (Entrez)23410
RRIDAB_3677416
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IP, ELISA
Working DilutionsWB:1:1000 - 1:4000 | IHC-P:1:500 - 1:2000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC51526
Molecular Weight28kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control.
Synonyms
SIR2L3; T3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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