[KO Validated] SOD2 Rabbit mAb,ABclonal,A19576

Reactivity

Human, Mouse, Rat

Application

WB, IF-P, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB718634414

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

Name[KO Validated] SOD2 Rabbit mAb
Cat. No.A19576
Accession NumberP04179
Gene ID (Entrez)6648
RRIDAB_2862677
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF-P, IHC-P, ELISA
Working DilutionsWB:1:10000 - 1:60000 | IF-P:1:200 - 1:800 | IHC-P:1:200 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC0055
Molecular Weight22kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.

Synonyms

GC1; IPOB; IPO-B; MNSOD; MVCD6; GClnc1; Mn-SOD; D2

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