[KO Validated] Src Rabbit mAb,ABclonal,A19119
Reactivity
Human, Mouse, Rat
Application
WB, IP, IF/ICC, IHC-P, ELISA
Conjugate
Unconjugated
Platform ID
BAB030840805
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
Name[KO Validated] Src Rabbit mAb
Cat. No.A19119
Accession NumberP12931
Gene ID (Entrez)6714
RRIDAB_2862612
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, IF/ICC, IHC-P, ELISA
Working DilutionsWB:1:1000 - 1:2000 | IP:0.5μg-4μg antibody for 400μg-600μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL | IF/ICC:1:100 - 1:400 | IHC-P:1:200-1:400. Please optimize the concentration based on your specific assay requirements.For high-ratio antibody dilutions (≥1:10000)，a sequential dilution method is strongly recommended to ensure measurement accuracy.
Clone NumberARC0378
Molecular Weight60kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Synonyms
ASV; SRC1; THC6; c-SRC; p60-Src; rc
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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