[KO Validated] TRIM21/SS-A Rabbit mAb,ABclonal,A22724

Reactivity

Human

Application

WB, ELISA

Conjugate

Unconjugated

Platform ID

BAB656652915

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Name[KO Validated] TRIM21/SS-A Rabbit mAb
Cat. No.A22724
Accession NumberP19474
Gene ID (Entrez)6737
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:1000 - 1:5000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC57363
Molecular Weight50kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Synonyms

SSA; RO52; SSA1; RNF81; Ro/SSA; -A

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