[KO Validated] YAP1 Rabbit mAb,ABclonal,A21216
Reactivity
Human, Mouse, Rat
Application
WB, IHC-P, IF/ICC, IP, ELISA, ChIP
Conjugate
Unconjugated
Platform ID
BAB093721872
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
Name[KO Validated] YAP1 Rabbit mAb
Cat. No.A21216
Accession NumberP46937
Gene ID (Entrez)10413
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, IP, ELISA, ChIP
Working DilutionsWB:1:20000 - 1:80000 | IHC-P:1:200 - 1:800 | IF/ICC:1:200 - 1:800 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | ChIP:5μg antibody for 10μg-15μg of Chromatin
Clone NumberARC53479
Molecular Weight70kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
YAP; YKI; COB1; YAP2; YAP-1; YAP65; P1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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