KSHV ORF73 antibody [AT4C11],Genetex,GTX50023

Host

Mouse

Reactivity

Kaposi's sarcoma-associated herpesvirus

Application

WB IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB428173902

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameKSHV ORF73 antibody [AT4C11]
Cat. No.GTX50023
HostMouse
IsotypeIgG2a
ReactivityKaposi's sarcoma-associated herpesvirus
ConjugationUnconjugated
ApplicationWB IHC-P ELISA
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenRecombinant human ORF73/HHV8 (122-329aa) purified from E. coli
PurityBy protein-G affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

ORF73 protein of human herpesvirus 8(HHV-8) is a kaposi's sarcoma-associated herpesvirus (kSHV) latent protein which has been suspected of playing a crucial role in modulating viral and cellular gene expression. ORF73 is associated with cellular chromatin and stays on the chromosomes during cell division. It maintains the viral genomes during cell division by tethering the viral episomes to the chromosomes. It binds directly to replication origin recognition complexes (ORCs) that are primarily associated with the terminal repeat (TR) region of the HHV-8 genome.

Synonyms

Kaposi's sarcoma-associated herpesvirus ORF73 , HHV-8 ORF73 , Human herpesvirus 8 ORF73

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