Kinase Suppressor of Ras 2 (KSR2) Antibody,Abbexa,abx026265

Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB, IHC, FCM

Conjugate

Unconjugated

Platform ID

BAB558391598

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameKinase Suppressor of Ras 2 (KSR2) Antibody
Cat. No.abx026265
Accession NumberQ6VAB6
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB, IHC, FCM
Working DilutionsWB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 108 kDa
TargetKSR2
ImmunogenKLH-conjugated synthetic peptide between 603-638 amino acids from the C-terminal region of human KSR2.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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