Klotho antibody, Internal,Genetex,GTX89443

Host

Goat

Reactivity

Human

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB524627582

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameKlotho antibody, Internal
Cat. No.GTX89443
Gene ID (Entrez)9365
HostGoat
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.50 mg/ml (Please refer to the vial label for the specific concentration.)
TargetKL
ImmunogenPeptide with sequence C-KRDDAKYMYYLKK, from the internal region of the protein sequence according to NP_004786.2; NP_710150.1.
PurityPurified by ammonium sulphate precipitation followed by antigen affinity chromatography
Appearance/FormLiquid
FormulationTBS, 0.5% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008]

Synonyms

klotho , HFTC3

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