Ku70 antibody [7B1],Genetex,GTX66844

Host

Mouse

Reactivity

Human, Monkey

Application

WB ICC/IF IP

Conjugate

Unconjugated

Platform ID

BAB609009588

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameKu70 antibody [7B1]
Cat. No.GTX66844
Gene ID (Entrez)2547
HostMouse
IsotypeIgG
ReactivityHuman, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IP
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetXRCC6
ImmunogenPurified recombinant human Ku70 protein fragments expressed in E.coli.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
Formulation100mM Tris-Glycine, 150mM NaCl, 50% Glycerol,0.2% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

Synonyms

X-ray repair cross complementing 6 , CTC75 , CTCBF , G22P1 , KU70 , ML8 , TLAA

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