Ku70 antibody [N3H10],Genetex,GTX23114

Host

Mouse

Reactivity

Human, Mouse, Hamster, Monkey, Xenopus laevis

Application

WB ICC/IF IHC-P IP

Conjugate

Unconjugated

Platform ID

BAB989117164

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameKu70 antibody [N3H10]
Cat. No.GTX23114
Gene ID (Entrez)2547
HostMouse
IsotypeIgG2b
ReactivityHuman, Mouse, Hamster, Monkey, Xenopus laevis
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IP
ClonalityMonoclonal
Concentration0.2 mg/ml (Please refer to the vial label for the specific concentration.)
TargetXRCC6
ImmunogenHuman placental extract designated as PSE1-PL.
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS, 0.2% BSA,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

Synonyms

X-ray repair cross complementing 6 , CTC75 , CTCBF , G22P1 , KU70 , ML8 , TLAA

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