Lamin B1 Antibody (YA3871),MedChemexpress,HY-P84174

Lamin B1 Antibody (YA3871) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LMNB1. It can be used as a loading control antibody.

Host

Mouse

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,ICC/IF,FC,ELISA

Conjugate

Non-conjugated

Platform ID

BAB399569249

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
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MedChemexpress

Master of Bioactive Molecules

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Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NameLamin B1 Antibody (YA3871)
Cat. No.HY-P84174
Accession NumberP20700 
Gene ID (Entrez)4001
HostMouse
RRIDAB_3718853
IsotypeIgG1
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,FC,ELISA
Working DilutionsWB: 1:500-1:2000; IHC-P: 1:200-1:1000; ICC/IF: 1:200-1:1000; FC: 1:200-1:400; ELISA: 1:10000
ClonalityMonoclonal Antibody
Clone NumberYA3871
Molecular WeightPredicted band size: 66 kDa; Observed band size: 66 kDa
ImmunogenPurified recombinant fragment of human LMNB1 (AA: 413-583) expressed in HEK293-6e cells supernatant.
Purityaffinity purified.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS with 0.05% sodium azide
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Lamin B1 is an intermediate filament protein that assembles into a filamentous meshwork and constitutes a major component of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Lamins provide a structural framework for the nuclear envelope, bridging it with chromatin, and play a crucial role in nuclear assembly, chromatin organization, nuclear membrane dynamics, and telomere regulation. The structural integrity of the lamina is tightly controlled by the cell cycle, as evidenced by the disassembly and reassembly of the nuclear envelope during prophase and telophase, respectively. by similar: Lamins are key members of the intermediate filament protein family, essential for maintaining nuclear structure and function.

Synonyms

LMN; ADLD; LMN2; LMNB; MCPH26

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