Langerin antibody [N2C3],Genetex,GTX116461

Host

Rabbit

Reactivity

Human, Mouse

Application

WB

Conjugate

Unconjugated

Platform ID

BAB450785572

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameLangerin antibody [N2C3]
Cat. No.GTX116461
Gene ID (Entrez)50489
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration0.94 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCD207
ImmunogenRecombinant protein encompassing a sequence within the Extracellular domain of human Langerin. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. [provided by RefSeq]

Synonyms

CD207 molecule , CLEC4K

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