Livin antibody [1D12],Genetex,GTX84823
Host
Mouse
Reactivity
Human, Mouse
Application
WB IHC-P FCM
Conjugate
Unconjugated
Platform ID
BAB134647276
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NameLivin antibody [1D12]
Cat. No.GTX84823
Gene ID (Entrez)79444
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB IHC-P FCM
ClonalityMonoclonal
Concentration0.36 mg/ml (Please refer to the vial label for the specific concentration.)
TargetBIRC7
ImmunogenFull length human recombinant protein of human BIRC7 (NP_071444) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.
Synonyms
baculoviral IAP repeat containing 7 , KIAP , LIVIN , ML-IAP , MLIAP , RNF50
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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