Lymphotoxin beta antibody, N-term,Genetex,GTX46565

Host

Rabbit

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB730085237

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameLymphotoxin beta antibody, N-term
Cat. No.GTX46565
Gene ID (Entrez)4050
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetLTB
ImmunogenA synthetic peptide corresponding to a N-terminal region of Human Lymphotoxin beta.
PurityAffinity Purified
Appearance/FormLiquid
FormulationPBS, 2% Sucrose,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Synonyms

lymphotoxin beta , TNFC , TNFSF3 , TNLG1C , p33

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