MACC1 antibody,Genetex,GTX131332

Host

Rabbit

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB843264678

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameMACC1 antibody
Cat. No.GTX131332
Gene ID (Entrez)346389
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration1.14 mg/ml (Please refer to the vial label for the specific concentration.)
TargetMACC1
ImmunogenRecombinant protein encompassing a sequence within the N-terminus region of human MACC1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM]

Synonyms

MET transcriptional regulator MACC1 , 7A5 , SH3BP4L

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