MACC1 antibody,Genetex,GTX131332
Host
Rabbit
Reactivity
Human
Application
WB
Conjugate
Unconjugated
Platform ID
BAB843264678

Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
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Product Specifications
Scientific Background
Synonyms
Specifications
NameMACC1 antibody
Cat. No.GTX131332
Gene ID (Entrez)346389
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration1.14 mg/ml (Please refer to the vial label for the specific concentration.)
TargetMACC1
ImmunogenRecombinant protein encompassing a sequence within the N-terminus region of human MACC1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM]
Synonyms
MET transcriptional regulator MACC1 , 7A5 , SH3BP4L
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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