MAP3K7 (pS192) Antibody,Abbexa,abx031952

MAP3K7 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.

Host

Rabbit

Reactivity

Human

Application

ELISA, DB

Conjugate

Unconjugated

Platform ID

BAB919829289

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameMAP3K7 (pS192) Antibody
Cat. No.abx031952
Accession NumberO43318
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, DB
Working DilutionsDB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 67.2 kDa
ImmunogenKLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S192 of human MAP3K7.
PurityPurified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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