MAdCAM-1 antibody [314G8] (Biotin),Genetex,GTX43836

Host

Mouse

Reactivity

Human

Application

ELISA

Conjugate

Biotin

Platform ID

BAB531246932

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameMAdCAM-1 antibody [314G8] (Biotin)
Cat. No.GTX43836
Gene ID (Entrez)8174
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationBiotin
ApplicationELISA
ClonalityMonoclonal
Concentration0.1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetMADCAM1
ImmunogenRecombinant soluble MAdCAM-1-fc fusion protein.
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS, 1% BSA,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Synonyms

mucosal vascular addressin cell adhesion molecule 1 , MACAM1

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