MBTPS2 antibody,Genetex,GTX86983

Host

Rabbit

Reactivity

Human

Application

ICC/IF

Conjugate

Unconjugated

Platform ID

BAB639095140

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameMBTPS2 antibody
Cat. No.GTX86983
Gene ID (Entrez)51360
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetMBTPS2
ImmunogenThe antiserum was produced against synthesized peptide derived from human MBTPS2 (301-350).
PurityPurified by antigen-affinity chromatographyFrom serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009]

Synonyms

BRESEK , IFAP , KFSD , KFSDX , MBTPS2 , OLMSX , S2P , membrane bound transcription factor peptidase, site 2

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