MCM3 antibody,Genetex,GTX24460

Host

Rabbit

Reactivity

Human, Xenopus

Application

WB IHC-P IP PLA

Conjugate

Unconjugated

Platform ID

BAB427885305

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameMCM3 antibody
Cat. No.GTX24460
Gene ID (Entrez)4172
HostRabbit
IsotypeIgG
ReactivityHuman, Xenopus
ConjugationUnconjugated
ApplicationWB IHC-P IP PLA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetMCM3
ImmunogenA 38-amino acid synthetic peptide, which represented a portion of human Minichromosome Maintenance Deficient 3 encoded in part by exons 10 and 11 (LocusLink ID 4172).
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationTris-Citrate/Phosphate,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq]

Synonyms

minichromosome maintenance complex component 3 , HCC5 , P1-MCM3 , P1.h , RLFB

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.