MCP1 / CCL2 antibody [ECE.2],Genetex,GTX54381

Host

Rat

Reactivity

Mouse

Application

WB IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB004398561

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameMCP1 / CCL2 antibody [ECE.2]
Cat. No.GTX54381
Gene ID (Entrez)20296
HostRat
IsotypeIgG1
ReactivityMouse
ConjugationUnconjugated
ApplicationWB IHC-Fr
ClonalityMonoclonal
Concentration100 μg/ml (Please refer to the vial label for the specific concentration.)
TargetCcl2
ImmunogenSynthetic peptide corresponding to residues 102-130 of mouse MCP-1
PurityProtein G purified
Appearance/FormLiquid
FormulationFilter-sterilized PBS, 0.1% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. [provided by RefSeq, Sep 2015]

Synonyms

chemokine (C-C motif) ligand 2 , AI323594 , HC11 , JE , MCAF , MCP-1 , MCP1 , SMC-CF , Scya2 , Sigje

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