MDC antibody,Genetex,GTX27363

Host

Rabbit

Reactivity

Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB119976850

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameMDC antibody
Cat. No.GTX27363
HostRabbit
IsotypeIgG
ReactivityRat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenRecombinant full length protein (Rat).
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

MDC (macrophage-derived chemokine) is a 69-amino acid CC chemokine with a NH2-terminalsequence of 24 residues as a signal sequence. It was originally cloned from human monocyte-derived macrophages (ref 1). Recombinant MDC attracts monocyte-derived dendritic cells, activated lymphocytes and natural killer cells (ref 1,2). MDC has anti-HIV-1 activity (ref 2). Expression of MDC mRNA in macrophages is enhanced by LPS, IL-1 and TNF (ref 3). MDC is a functional ligand for CCR4 (ref 4).

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