MEK1 (phospho Ser217) + MEK2 (phospho Ser221) antibody [HL4054],Genetex,GTX642469

Host

Rabbit

Reactivity

Human, Mouse

Application

WB

Conjugate

Unconjugated

Platform ID

BAB844841392

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameMEK1 (phospho Ser217) + MEK2 (phospho Ser221) antibody [HL4054]
Cat. No.GTX642469
Gene ID (Entrez)5604
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetMAP2K1
ImmunogenCarrier-protein conjugated synthetic peptide surrounding phospho Ser217 of human MEK1. The exact sequence is proprietary.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]

Synonyms

mitogen-activated protein kinase kinase 1 , CFC3 , MAPKK1 , MEK1 , MKK1 , PRKMK1

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