MKL1 Rabbit pAb- ABclonal,ABclonal,A12598
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Conjugate
Unconjugated
Platform ID
BAB710926851
ABclonal
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Product Specifications
Scientific Background
Specifications
NameMKL1 Rabbit pAb- ABclonal
Cat. No.A12598
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight145kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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