MLH1 antibody [4C9C7],Genetex,GTX83336

Host

Mouse

Reactivity

Human, Monkey

Application

WB ICC/IF IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB130349340

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameMLH1 antibody [4C9C7]
Cat. No.GTX83336
Gene ID (Entrez)4292
HostMouse
IsotypeIgG1
ReactivityHuman, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P ELISA
ClonalityMonoclonal
TargetMLH1
ImmunogenPurified recombinant fragment of MLH1 (aa381-483) expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]

Synonyms

mutL homolog 1 , COCA2 , FCC2 , HNPCC , HNPCC2 , hMLH1

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