MLLT11 antibody,Genetex,GTX52000

Host

Rabbit

Reactivity

Human

Application

ELISA

Conjugate

Unconjugated

Platform ID

BAB057584284

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameMLLT11 antibody
Cat. No.GTX52000
Gene ID (Entrez)10962
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetMLLT11
ImmunogenKLH conjugated synthetic peptide derived from human MLLT11.
PurityProtein A purified
Appearance/FormLiquid
Formulation1% BSA, 50% Glycerol,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008]

Synonyms

MLLT11 transcription factor 7 cofactor , AF1Q

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