MMP-9 Antibody (YA285),MedChemexpress,HY-P80425

MMP-9 Antibody (YA285) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP-9.

Host

Rabbit

Reactivity

Human,Rat

Application

WB,IHC-P,ICC/IF,FC,IF-Tissue

Conjugate

Non-conjugated

Platform ID

BAB627704749

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameMMP-9 Antibody (YA285)
Cat. No.HY-P80425
Accession NumberP14780
Gene ID (Entrez)4318
HostRabbit
RRIDAB_3102508
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,FC,IF-Tissue
Working DilutionsWB: 1:5000; ICC/IF: 1:50-1:200; IHC-P: 1:200-1:1000; FC: 1:50-1:100; IF-Tissue: 1:50-1:200
ClonalityRecombinant,Monoclonal
Clone NumberYA285
Molecular WeightPredicted band size: 78 kDa; Observed band size: 92 kDa
ImmunogenSynthetic peptide corresponding to Human MMP9.AA range:71-120.
PurityProtein A affinity purified.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

MMP-9 Protein, a matrix metalloproteinase, plays a crucial role in local proteolysis of the extracellular matrix and facilitates leukocyte migration. It could be involved in bone osteoclastic resorption and cleaves KiSS1 at a specific Gly-|-Leu bond. Additionally, MMP-9 cleaves NINJ1 to generate the Secreted ninjurin-1 form and processes type IV and type V collagen into large C-terminal three-quarter fragments and shorter N-terminal one-quarter fragments. While degrading fibronectin, MMP-9 does not impact laminin or Pz-peptide, showcasing its selectivity in substrate cleavage.

Synonyms

MMP-9; GELB; MMP9; CLG4B

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