MMP14 Recombinant Antibody,Bioss,bsm-52373r-TR

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF

Conjugate

Unconjugated

Platform ID

BAB602621161

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameMMP14 Recombinant Antibody
Cat. No.bsm-52373r-TR
Accession NumberP50281
Gene ID (Entrez)4323
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF
Working DilutionsWB:1:300-5000 | IHC-P:1:200-400 | IHC-F:1:100-500 | IP:1-2ug | IF: | Flow-Cyt:1ug/Test | ICC/IF:1:50-100
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.

Synonyms

Matrix metalloproteinase-14, MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP-14, MTMMP1, MT1-MMP, MT1MMP, MT-MMP 1

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