MMP23 antibody,Genetex,GTX11645

Host

Rabbit

Reactivity

Human

Application

WB IHC-Fr IP ELISA

Conjugate

Unconjugated

Platform ID

BAB513266831

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameMMP23 antibody
Cat. No.GTX11645
Gene ID (Entrez)8510
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-Fr IP ELISA
ClonalityPolyclonal
Concentration~1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetMMP23B
Immunogensynthetic peptide corresponding to the C-terminal of human matrix metalloproteinase-23 (MIFR-2, CA-MMP).
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 50% Glycerol,15mM Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Matrix Metalloproteinase 23 (MMP21, MMP22, MIFR2, CAMMP) was first described in tumor cells. MMP23 shares much of the same domain structure as the classical MMPs, but has a unique cysteine array. The cysteine switch that is found in the classical MMPs is lacking or has a different sequence in MMP23. MMP23 has a furin cleavage site and it is thought to be localized within the cell. MMP23 has been reported as splice variants with different truncations at its C-terminus. MMP23 is predominantly expressed in ovary, testis, and prostate indicating that it plays a specialized role in reproductive processes. The human MMP23 gene has the chromosomal location of 1p36.3. The chromosome 1 location is a unique position among all the MMP genes currently mapped.

Synonyms

matrix metallopeptidase 23B , MIFR , MIFR-1 , MMP22 , MMP23A

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