MOB1A/MOB1B Rabbit pAb- ABclonal,ABclonal,A18246

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, ELISA

Platform ID

BAB956154143

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameMOB1A/MOB1B Rabbit pAb- ABclonal
Cat. No.A18246
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationWB, IF/ICC, ELISA
Working DilutionsWB:1:500 - 1:2000 | IF/ICC:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight24kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein MOB1 is considered to be one of the core components of the mammalian Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. MOB1A and MOB1B, which have 95% sequence identity, play redundant biological roles and are both termed MOB1.

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