MRPS31 Antibody (YA3246),MedChemexpress,HY-P83501

Mammalian mitochondrial ribosomal proteins are encoded by nuclear related genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where The ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. The related gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of The disease remains to be clarified. Pseudorelated genes corresponding to The related gene have been found on chromosomes 3 and 13.

S31mt; IMOGN38; MRP-S31