Mannose Receptor/CD206 Rabbit pAb- ABclonal,ABclonal,A25433

Reactivity

Human, Rat

Application

WB, IF-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB578268029

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameMannose Receptor/CD206 Rabbit pAb- ABclonal
Cat. No.A25433
RRID#N/A
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB, IF-P, ELISA
Working DilutionsWB:1:500 - 1:5000 | IF-P:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight170-250 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.

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