Mast cell chymase antibody [CC1],Genetex,GTX73841

Host

Mouse

Reactivity

Human, Mouse

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB736670810

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameMast cell chymase antibody [CC1]
Cat. No.GTX73841
Gene ID (Entrez)1215
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetCMA1
ImmunogenBALB/C mice were injected with a purified human skin Chymase.
PurityPurified IgG
Appearance/FormLiquid
Formulation,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015]

Synonyms

chymase 1 , CYH , MCT1 , chymase

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