Melanoma gp100 antibody [7B2],Genetex,GTX83639

Host

Mouse

Reactivity

Human

Application

ICC/IF FCM

Conjugate

Unconjugated

Platform ID

BAB506336366

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameMelanoma gp100 antibody [7B2]
Cat. No.GTX83639
Gene ID (Entrez)6490
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF FCM
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPMEL
ImmunogenFull length human recombinant protein of human SILV (NP_008859) produced in HEK293T cell.
PurityPurified by affinity chromatographyFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Synonyms

premelanosome protein , D12S53E , ME20 , ME20-M , ME20M , P1 , P100 , PMEL17 , SI , SIL , SILV , gp100

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