Melanoma gp100 antibody [8A4],Genetex,GTX83640
Host
Mouse
Reactivity
Human, Rat, Dog, Monkey
Application
WB ICC/IF IHC-P
Conjugate
Unconjugated
Platform ID
BAB818842613
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NameMelanoma gp100 antibody [8A4]
Cat. No.GTX83640
Gene ID (Entrez)6490
HostMouse
IsotypeIgG2b
ReactivityHuman, Rat, Dog, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPMEL
ImmunogenFull-length protein expressed in 293T cell transfected with human SILV expression vector
PurityPurified by affinity chromatographyFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Synonyms
premelanosome protein , D12S53E , ME20 , ME20-M , ME20M , P1 , P100 , PMEL17 , SI , SIL , SILV , gp100
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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