Mesothelin Rabbit mAb,ABclonal,A21982

Reactivity

Human

Application

WB, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB601867960

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameMesothelin Rabbit mAb
Cat. No.A21982
Accession NumberQ13421
Gene ID (Entrez)10232
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IHC-P, ELISA
Working DilutionsWB:1:2000 - 1:20000 | IHC-P:1:1000 - 1:5000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC54390
Molecular Weight40kDa/69kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Synonyms

MPF; SMRP; Mesothelin

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